Drug Study (ranitidine, metoclopramide, ketorolac, and omeprazole)

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...a complete detail of drug study for ranitidine, omeprazole, metoclopramide, and ketorolac...
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  DRUGDOSEROUTEINDICATIONSCONTRAINDICATIONACTIONSIDEEFFECT NURSINGCONSIDERATIONSGeneric Name:RanitidineHydrochlorideBrand Name:ZantacClass:Histamine 2 antagonists50 mgq 8hrsIVShort-termtreatment of active duodenalulcer Short-termtreatment of active, benigngastric ulcer Maintenancetherapy for duodenal ulcer at reduceddosage.Short-termtreatment for GERD.Pathologichypersecretoryconditions(Zollinger-Ellisonsyndrome)Contraindicated withallergy to ranitidine,lactationUse cautiously withimpaired renal or hepaticfunction, pregnancyCompetitivelyinhibits theaction of histamine atthe H 2 receptors of the parietalcells of thestomach,inhibiting basal gastricacid secretionand gastricacid secretionthat isstimulated byfood, insulin,histamine,cholinergicagonists,gastrin and pentagastrin.CNS:headache,malaise,dizziness,somnolence,insomnia,vertigoCV:tachycardia, bradycardiaDermatologic:rash, alopeciaGI:constipation,diarrhea,nausea andvomiting,abdominal pain, hepatitisGU:impotence or decreasedlibidoAssessment:1. History: allergy toranitidine, impairedrenal or hepaticfunction, lactation, pregnancy.2. Physical: skinlesions, orientation,affect, liver evaluation,abdominalexamination, normaloutput, renalfunction tests, CBCInterventions:1. Administer oraldrug with meals andat bedtime.2. Decrease doses inrenal and liver failure.3. Provideconcurrent antacidtherapy to relieve pain.4. Administer IM  Treatment of erosiveesophagitisTreatment of heartburn, acidindigestion,sour stomachHematologic:leucopenia,granulocytopenia,thrombocytopenia, pancytopeniadose undiluted, deepinto large musclegroup.5. Arrange for regular follow-upincluding blood test,to evaluate effects.  DRUGDOSEROUTEINDICATIONSCONTRAINDICATIONSACTIONSIDEEFFECT NURSINGCONSIDERATIONSGeneric Name:MetoclopramideBrand Name:MaxolonClass:Antiemetic, GIstimulant1 ampq 8 hrsIVDisturbances of GI motilityRelief of symptoms of acute andrecurrentdiabeticgastroparesis Nausea andvomitingMetabolicdiseasesShort-termtherapy for adults withsymptomaticgastroesophageal reflux whofail to respondto conventionaltherapy.Contraindicated withallergy to metoclopramideGI hemorrhageMechanical obstruction or  perforationEpilepsyUse cautiously with previously detected breastcancer, lactation, pregnancy, fluid overload,renal impairmentStimulatesmotility of upper GItract withoutstimulatinggastric, biliary, or  pancreaticsecretions;appears tosensitizetissues toaction of acetylcholine; relaxes pyloricsphincter,which,whencombinedwith effectson motility,acceleratesgastricemptyingCNS:restlessness,drowsiness,fatigue,insomnia,dizziness,anxietyCV:transienthypertensionGI: nauseaand diarrheaAssessment:1. History: allergy tometoclopramide, GIhemorrhage,mechanicalobstruction or  perforation,depression, epilepsy,lactation, previouslydetected breast cancer 2. Physical:orientation, reflexes,affect, bowel sounds,normal output, EEGInterventions:1. Monitor BPcarefully during IVadministration.2. Monitor diabetic patients, arrange for alterations in insulindose or timing if diabetic control iscompromised by  Prophylaxis of  postoperativenausea andvomiting whennasogastricsuction isundesirable.andintestinaltransit; littleeffect ongallbladder or colonmotility;increaseslower esophagealsphincter  pressure;has sedative properties;inducesrelease of  prolactinalterations in timingof food absorption.
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